| Univariate analysis |  | Multivariate analysis* |  | ||
---|---|---|---|---|---|---|
 | Odds ratio (95% CI) |  |  | Odds ratio (95% CI) |  |  |
 |  | p value | Wald chi 2 |  | p value | Wald chi 2 |
Age at screening | Â | Â | Â | Â | Â | Â |
Age 16-20 | 1 | Â | Â | 1 | Â | Â |
Age 21-25 | 1.65 (1.11-2.48) | 0.014 | 2.45 | 1.76 (1.06-2.91) | 0.03 | 2.21 |
Age 26-30 | 2.01 (1.25-3.23) | 0.004 | 2.89 | 0.87 (0.45-1.69) | 0.68 | -0.41 |
Age 31-35 | 6.52 (3.43-12.39) | < 0.001 | 5.72 | 1.16 (0.37-3.64) | 0.79 | 0.26 |
Years of education | Â | Â | Â | Â | Â | Â |
< 10 years | 1 | Â | Â | 1 | Â | Â |
10-12 years | 1.11(0.68-1.81) | 0.68 | 0.41 | 0.91 (0.52-1.60) | 0.75 | -0.32 |
> 12 years | 1.07 (0.63-1.81) | 0.81 | 0.24 | 0.91 (0.50-1.67) | 0.76 | -0.30 |
Family history of substance use | Â | Â | Â | Â | Â | Â |
Absent | 1 | Â | Â | 1 | Â | Â |
Present | 2.29 (1.57-3.37) | < 0.001 | 4.26 | 2.36 (1.39-4.01) | 0.002 | 3.16 |
Duration of use (years) | Â | Â | Â | Â | Â | Â |
< 6 years | 1 | Â | Â | 1 | Â | Â |
6-10 years | 2.87 (1.90-4.33) | < 0.001 | 5.02 | 3.62 (2.16-6.07) | < 0.001 | 4.89 |
> 10 years | 5.88 (2.91-11.91) | < 0.001 | 4.92 | 7.18 (2.08-24.82) | 0.002 | 3.12 |
Group | Â | Â | Â | Â | Â | Â |
Areca only | 1 | Â | Â | 1 | Â | Â |
Areca with tobacco additives | 1.74 (1.18-2.56) | 0.005 | 2.82 | 2.17 (1.39-3.40) | 0.001 | 3.4 |
Smokers only | 4.31 (2.76-6.73) | < 0.001 | 6.44 | 7.87 (4.70-13.15) | < 0.001 | 7.87 |