| Buprenorphine (n = 52) | Methadone (n = 52) | Group comparison p-values |
---|---|---|---|
Opioid agonist drug (M ± SD) | 20 ± 6 mg | − | − |
Buprenorphine (M ± SD) | − | 113 ± 49 mg |  |
Patients using any psychoactive medication, other than opioid | 42 (81%) | 43 (83%) | p = 1.00 |
Patients using any BDZ drug | 37 (71%) | 38 (73%) | p = 1.00 |
diazepam | 29 (56%) | 24 (46%) | p = .43 |
oxazepam | 8 (15%) | 14 (27%) | p = .15 |
Benzodiazepine, diazepam equivalent dose (M ± SD) | 22 ± 10 mg | 21 ± 10 mg | p = 0.77 |
The number psychoactive drugs, other than opioid or BZDa | Â | Â | Â |
(M ± SD) | 1.2 ± 1.2 | 1.2 ± 1.2 | p = .81 |
0, no. patients (%) | 18 (35%) | 19 (36%) | p = 1.00 |
1 no. patients (%) | 19 (37%) | 13 (25%) | p = .29 |
2 no. patients (%) | 9 (17%) | 13 (25%) | p = .47 |
3 no. patients (%) | 2 (4%) | 5 (10%) | p = .44 |
4 or more no. patients (%) | 4 (7%) | 2 (4%) | p = .68 |
Patients using psychoactive drug, other than opioid or BZD | Â | Â | Â |
Any drugb | 34 (65%) | 33 (63%) | p = 1.00 |
Anticonvulsants | 6 (12%) | 5 (10%) | p = 1.00 |
Antidepressants | 22 (42%) | 13 (25%) | p = .096 |
Antihistamines | 6 (12%) | 10 (19%) | p = .42 |
Neuroleptics | 7 (13%) | 9 (17%) | p = .79 |
Non-Benzodiazepine hypnotics | 16 (31%) | 19 (37%) | p = .68 |
Non-opioid pain killers | 4 (8%) | 6 (12%) | p = .74 |