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Table 3 Risk of relapse after the index substance use for related variables estimated by Cox proportional hazards model

From: Difference in long-term relapse rates between youths with ketamine use and those with stimulants use

Variables

Relapse

Unadjusted model

Adjusted model

n/N (%)

HR (95% CI)

P-value

aHR (95% CI)

P-value

Age (years)

–

0.91 (0.72–1.16)

0.450

1.00 (0.77–1.28)

0.968

Gender

 Male

47/104 (45.2)

1

 

1

 

 Female

11/31 (35.5)

0.83 (0.43–1.60)

0.577

0.89 (0.45–1.77)

0.735

Substance use

 Ketamine

32/92 (34.8)

1

 

1

 

 Stimulants

26/43 (60.5)

1.58 (0.93–2.68)

0.090

1.86 (1.06–3.28)

0.032*

Previous conviction record

 Without

36/94 (38.3)

1

 

1

 

 With

22/41 (53.7)

1.48 (0.87–2.51)

0.152

1.56 (0.91–2.67)

0.106

Academic or social status

 Employed

12/42 (28.6)

1

 

1

 

 Attending school

22/43 (51.2)

2.23 (1.10–4.52)

0.025*

2.77 (1.28–6.02)

0.010*

 Dropout and unemployed

24/50 (48.0)

2.06 (1.03–4.12)

0.042*

1.99 (0.97–4.08)

0.061

Family status

 Double-parent families

26/61 (42.6)

1

 

1

 

 Single-parent families

26/58 (44.8)

1.15 (0.67–1.97)

0.624

1.16 (0.66–2.02)

0.608

 Grandparent(s)

6/16 (37.5)

0.81 (0.33–1.97)

0.637

0.72 (0.28–1.86)

0.492

  1. Stimulants: methamphetamine or MDMA; HR: unadjusted hazard ratio; aHR: adjusted hazard ratio; 95% CI, 95% confidence interval; n, number of individuals who relapsed with substance use; N, number of total subjects; *p < 0.05