Table 1 General characteristics of the study participants1
|  | Placebo group (n = 25) | Crocin group (n = 25) | P 2 |
|---|---|---|---|
Age (y) | 41.4 ± 8.8 | 40.1 ± 9.3 | 0.63 |
Height (cm) | 171.2 ± 7.5 | 171.6 ± 8.4 | 0.84 |
Weight at study baseline (kg) | 70.1 ± 8.5 | 68.9 ± 12.1 | 0.68 |
Weight at the end-of-trial (kg) | 69.7 ± 8.6 | 69.0 ± 11.7 | 0.81 |
Weight change (kg) | −0.4 ± 1.6 | 0.08 ± 1.4 | 0.23 |
BMI at study baseline (kg/m2) | 23.9 ± 2.9 | 23.3 ± 3.6 | 0.51 |
BMI at the end-of-trial (kg/m2) | 23.8 ± 3.0 | 23.4 ± 3.6 | 0.66 |
BMI change (kg/m2) | −0.1 ± 0.5 | 0.05 ± 0.5 | 0.19 |
Education (%) | |||
 Illiterate | 5 (20) | 7 (28) |  |
 Elementary | 5 (20) | 7 (28) |  |
 Intermediate | 12 (48) | 10 (40) | 0.58†|
 Diploma | 2 (8) | 0 (0) |  |
 High educated | 1 (4) | 1 (4) |  |
Marital status (%) | |||
 Single | 8 (32) | 5 (20) |  |
 Married | 5 (20) | 8 (32) | 0.50†|
 Widow/Divorced | 12 (48) | 12 (48) |  |
Job (%) | |||
 Unemployed | 16 (64) | 18 (72) |  |
 Employed | 2 (8) | 1 (4) | 0.76†|
 Others | 7 (28) | 6 (24) |  |
Use of other drugs (%) | |||
 None | 20 (80) | 19 (76) |  |
 Benzodiazepine | 2 (8) | 3 (12) | 0.89†|
 Antidepressants (SSRIs) | 3 (12) | 3 (12) |  |
 Methadone dose (mL/d) | 19.2 ± 6.2 | 17.2 ± 5.9 | 0.25 |
 Duration of MMT (y) | 6.2 ± 2.6 | 5.5 ± 1.9 | 0.33 |