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Table 1 Themes and sub-themes identified in the analysis

From: Patient perspectives on depot buprenorphine treatment for opioid addiction – a qualitative interview study

Theme

Sub-theme

Mentioned by

The effects and side effects of the depot-formulation

Withdrawal symptoms during induction period

Most patients

Other side effects during induction period

Some patients

Lasting withdrawal symptoms and drug cravings

Patients who had discontinued depot injections

Lumps at injection sites

Many patients, but mentioned as big problem by some who had discontinued depot injections

Social and practical factors

Freedom of not having to attend the clinic as frequently

Many patients, patients with employment

More time for family and leisure activities

Many patients

Benefit not having to handle medication

Patient who accepted depot injections

No social pressure to divert

Patient who accepted depot injections

Frequent clinic visits a routine that gives structure to everyday life

Patients who declined depot injections

Frequent clinic visits a valued social activity

Some patients

No practical benefits of depot injections

Some patients who collected their medication at pharmacies

Psychological benefits

A shift in self-perception – feeling more “free” and “normal”

Patient who accepted depot injections

A relief not having to think about the medication every day

Patient who accepted depot injections

Reduced drug stigma

Patient who accepted depot injections

The clinic as a risk environment – reduced exposure to patients in active drug use

Patient who accepted depot injections

Psychological disadvantages

Unwillingness and/or fear to change an effective medication

Patients who declined depot injections

Perceived need to take medication every day

Patients who declined depot injections

Depot injections perceived as untested with unknown side-effects

Patients who declined depot injections

Pharmaceutical atmosphere

Depot injections were introduced responsibly by staff

Most patients

Trustful relationships with staff important when deciding on medication

Many patients

Information and rumors among patients may influence perceptions of depot injections

Many patients

Coercion leads to dissatisfaction, mistrust and negative rumors

Patients at one clinic