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Table 2 Correlates of client outcomes regarding cannabis use (Abstinence and ≥ 50% Reductiona)

From: Correlates of treatment engagement and client outcomes: results of a randomised controlled trial of nabiximols for the treatment of cannabis use disorder

Variable

Abstinent

(n = 17)

Non-abstinent (n = 111)

ORb (95% CI)

 ≥ 50% reduction

(n = 31)

 < 50% reduction

(n = 97)

ORb 95% CI

Duration Regular Use, in decades, M (SD)

2.22 (1.12)

1.46 (0.87)

3.03 (1.36, 7.29)

1.84 (1.05)

1.47 (0.89)

2.87 (1.39, 6.60)

Gender, n (%)

 Female

9 (30.00)

21 (70.00)

4.12c (0.75, 24.30)

12 (40.00)

18 (60.00)

2.10c (0.49, 9.46)

 Male

8 (8.25)

89 (91.75)

19 (19.59)

78 (80.41)

 Non-binary

0 (0.00)

1 (100.00)

0 (0.00)

1 (100.00)

Treatment Groupd, n (%)

 Nabiximols

10 (16.39)

51 (83.61)

2.27 (0.50, 11.51)

20 (32.79)

41 (67.21)

4.06 (1.21, 14.95)

 Placebo

7 (10.45)

60 (89.55)

11 (16.42)

56 (83.58)

Average quantity of cannabis used, gms, M (SD)

1.89 (1.54)

2.41 (2.13)

0.91 (0.53, 1.42)

1.66 (1.44)

2.56 (2.19)

0.75 (0.46, 1.12)

Cannabis Problems Questionnaire, z, M (SD)

0.03 (1.13)

-0.00 (0.98)

0.72 (0.26, 1.97)

-0.04 (1.00)

0.01 (1.01)

0.96 (0.44, 2.09)

Self-Coping and Efficacy for Quitting, z, M (SD)

0.29 (1.29)

-0.04 (0.95)

1.50 (0.75, 3.15)

0.03 (1.18)

-0.01 (0.95)

0.85 (0.47, 1.53)

SF-36 Pain score, z, M (SD)

-0.55 (1.03)

0.08 (0.97)

0.41 (0.16, 1–01)

-0.22 (1.01)

0.07 (0.99)

0.40 (0.18, 0.83)

DASS Total Score, z, M (SD)

0.27 (1.03)

-0.04 (0.99)

0.98 (0.34, 2.79)

0.04 (1.08)

-0.01 (0.98)

0.65 (0.27, 1.50)

Insomnia Severity Index, z, M (SD)

0.19 (1.11)

-0.03 (0.98)

0.68 (0.26, 1.69)

-0.11 (1.09)

0.03 (0.97)

0.39 (0.18, 0.82)

Rate of Counselling Attendance, average number of sessions per fortnight (14 days), M (SD)

0.23 (0.22)

0.11 (0.27)

5.31 (1.45, 22.19)

0.18 (0.11)

0.11 (0.14)

3.82 (1.30, 12.15)

Average Dose weeks 2–12, sprays per day, M (SD)

14.58 (8.08)

18.70 (9.60)

0.92 (0.83, 1.01)

14.68 (8.95)

19.29 (9.41)

0.91 (0.84, 0.98)

  1. az-score = (raw score – mean)/sd for variable in question. For both the abstinence criteria and ≥ 50% reduction criteria there were two potential ways of meeting criteria for non-success: (i) using illicit cannabis at least once in the previous 28 days (ii) dropping out of the study early; that is, failing to complete the week 12 research interview
  2. bOR Odds ratio. Each coefficient represents the increase in odds of either abstinence during weeks 9-12or ≥ 50% reduction associated with a 1-unit increase in the covariate
  3. cfor analysis the gender variable was collapsed from a three-level categorical into a two-level categorical: male (ref) vs non-male (female n = 30 + non-binary n = 1)
  4. dplacebo (ref) vs nabiximols